Research
Detection of weakly conserved ancestral mammalian regulatory sequences by primate comparisons
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* Corresponding authors: Qian-fei Wang qwang2@medicine.bsd.uchicago.edu - Dario Boffelli DBoffelli@lbl.gov
- † Equal contributors
1 Genomics Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720 USA
2 US Department of Energy Joint Genome Institute, Walnut Creek, California 94598, USA
3 Current address: Section of Hematology/Oncology, Department of Medicine, University of Chicago, 5814 S. Ellis Avenue, Chicago, IL 60637, USA
Genome Biology 2007, 8:R1 doi:10.1186/gb-2007-8-1-r1
Published: 3 January 2007Additional files
Additional data file 1:
Sequence alignments of primate-conserved sequence LDLR_PS2.
Format: EPS Size: 4MB Download file
Additional data file 2:
Sequence alignments of primate-conserved sequence SREBF1_PS.
Format: EPS Size: 2.3MB Download file
Additional data file 3:
Luciferase functional assays, indicating enhancer activity for orthologous primate LDLR PS4 from baboon, dusky titi, marmoset and lemur.
Format: EPS Size: 1MB Download file
Additional data file 4:
Coordinates of evolutionarily conserved elements.
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Additional data file 5:
Sequences of PCR primers used for cloning regulatory elements into reporter gene constructs or generating Southern blotting probes for detecting. DNase I hypersensitive sites
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Additional data file 6:
GenBank accession numbers for all primate BACs sequenced.
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Additional data file 7:
Figure legends for Additional data files 1, 2, 3.
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