Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profiling
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* Corresponding author: Christopher C Goodnow chris.goodnow@anu.edu.au
Genome Biology 2007, 8:R12 doi:10.1186/gb-2007-8-1-r12
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Id1 induces apoptosis through inhibition of RORgammat expression Yuanzheng Yang, Hong-Cheng Wang, Xiao-Hong Sun BMC Immunology 2008, 9:20 (19 May 2008) Apoptosis of developing thymocytes caused by the transcription factor Id1 can be prevented by RORgamma-t expression, regulated in turn by E- protein transcription factors, suggesting an important biological link between these regulators in T-cell maturation.
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