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GENECODIS: a web-based tool for finding significant concurrent annotations in gene lists

Pedro Carmona-Saez1, Monica Chagoyen12, Francisco Tirado2, Jose M Carazo1 and Alberto Pascual-Montano2*

Author Affiliations

1 BioComputing Unit, National Center of Biotechnology (CNB-CSIC), C/Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain

2 Computer Architecture Department, Facultad de Ciencias Físicas, Universidad Complutense de Madrid, C/Avenida Complutense S/N, 28040 Madrid, Spain

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Genome Biology 2007, 8:R3  doi:10.1186/gb-2007-8-1-r3

Published: 4 January 2007

Abstract

We present GENECODIS, a web-based tool that integrates different sources of information to search for annotations that frequently co-occur in a set of genes and rank them by statistical significance. The analysis of concurrent annotations provides significant information for the biologic interpretation of high-throughput experiments and may outperform the results of standard methods for the functional analysis of gene lists. GENECODIS is publicly available at http://genecodis.dacya.ucm.es/ webcite.