Table 2 |
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|
Regulatory response to transcription factor deletion |
|||||||||||
| Genome wide |
B+/C+ |
B+/C- |
B-/C+ |
||||||||
|
|
|||||||||||
| Mean |
SD |
Mean |
SD |
P value |
Mean |
SD |
P value |
Mean |
SD |
P value |
|
|
|
|||||||||||
| Yap1 |
0.003 |
0.092 |
-0.174 |
0.23 |
7.24 × e-03 |
0.043 |
0.13 |
0.158 |
-0.104 |
0.16 |
6.31 × e-03 |
| Swi5 |
0.004 |
0.06 |
-0.1 |
0.166 |
3.71 × e-04 |
0.006 |
0.042 |
0.668 |
-0.019 |
0.03 |
1.01 × e-03 |
| Swi4 |
0.015 |
0.17 |
-0.124 |
0.24 |
1.23 × e-07 |
0.058 |
0.178 |
0.242 |
-0.067 |
0.156 |
3.29 × e-03 |
| Gcn4 |
-0.007 |
0.07 |
-0.26 |
0.22 |
2.57 × e-11 |
-0.002 |
0.032 |
0.421 |
-0.158 |
0.137 |
4.40 × e-03 |
|
|
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|
By conducting standard t-tests, the significance of the change in expression between knockout and wild-type was examined within each gene set (B+/C+, B-/C+, B+/C-) for four transcription factors for which expression, ChIP-ChIP, and deletion data are available. ChIP, chromatin immunoprecipitation; SD, standard deviation. |
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|
Chen et al. Genome Biology 2007 8:R4 doi:10.1186/gb-2007-8-1-r4 |
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