Table 2 |
||||||||
|
Scoring of immune infiltrate by immuno histochemistry |
||||||||
|
Pooled treatment groups |
Δ Score post - pre-treatment |
Within group p value |
||||||
|
|
||||||||
|
-3 |
-2 |
-1 |
0 |
1 |
2 |
3 |
||
|
|
||||||||
|
CD56 |
||||||||
|
Imiquimod |
0 |
0 |
1 |
12 |
6 |
1 |
0 |
0.03 |
|
Vehicle |
0 |
0 |
2 |
11 |
0 |
0 |
0 |
0.17 |
|
CD8 |
||||||||
|
Imiquimod |
0 |
0 |
1 |
10 |
7 |
1 |
1 |
0.01 |
|
Vehicle |
0 |
0 |
0 |
9 |
1 |
2 |
0 |
0.22 |
|
CD4 |
||||||||
|
Imiquimod |
0 |
0 |
1 |
12 |
7 |
0 |
0 |
0.03 |
|
Vehicle |
0 |
0 |
2 |
5 |
4 |
1 |
0 |
0.22 |
|
BCL-2 |
||||||||
|
Imiquimod |
0 |
0 |
1 |
11 |
6 |
2 |
0 |
0.02 |
|
Vehicle |
0 |
0 |
2 |
9 |
1 |
1 |
0 |
0.72 |
|
|
||||||||
|
P values associated with the paired t-test for within group shifts relative to baseline. Δ Score refers to differences in infiltrate between EOT and pre-treatment samples using the scoring scale described in Materials and methods (IHC section). |
||||||||
|
Panelli et al. Genome Biology 2007 8:R8 doi:10.1186/gb-2007-8-1-r8 |
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