Table 2

Gene Ontology annotation

Solenopsis invicta EST library
 D. melanogaster genome



Blastx-determined GO
 Prosite-determined GO
Molecular function
 4,301*
(100.0%)
 486*
(100.0%)
 14,778* (100.0%)
     Antioxidant activity
 20
(0.5%)
 2
(0.4%)
 39 (0.3%)
     Binding
 1,765
 ↑
 (41.0%)
 174
(35.8%)
 4,319 (29.2%)
     Catalytic activity
 1,456
 ↑
 (33.9%)
 201
 ↑
 (41.4%)
 4,072 (27.6%)
     Chaperone regulator activity
 5
 ↑
 (0.1%)
 0
(0.0%)
 1 (0.0%)
     Enzyme regulator activity
 91
(2.1%)
 7
(1.4%)
 382 (2.6%)
     Molecular function unknown
 145
 ↓
 (3.4%)
 6
 ↓
 (1.2%)
 1,852 (12.5%)
     Motor activity
 29
(0.7%)
 1
(0.2%)
 88 (0.6%)
     Nutrient reservoir activity
 14
 ↑
 (0.3%)
 0
(0.0%)
 8 (0.1%)
     Obsolete molecular function
 0
(0.0%)
 9
 ↑
 (1.9%)
 0 (0.0%)
     Signal transducer activity
 153
 ↓
 (3.6%)
 4
 ↓
 (0.8%)
 1,091 (7.4%)
     Structural molecule activity
 210
(4.9%)
 59
(12.1%)
 759 (5.1%)
     Transcription regulator activity
 116
 ↓
 (2.7%)
 4
(0.8%)
 841 (5.7%)
     Translation regulator activity
 62
 ↑
 (1.4%)
 7
(1.4%)
 92 (0.6%)
     Transporter activity
 235
(5.5%)
 12
(2.5%)
 1,014 (6.9%)
     Triplet codon-amino acid adaptor activity
 0
 ↓
 (0.0%)
 0
(0.0%)
 220 (1.5%)
Cellular component
 4,838*
(100.0%)
 362*
(100.0%)
 14,986* (100.0%)
     Cell†
 1,868
 ↑
 (38.6%)
 147
(40.6%)
 5,225 (34.9%)
     Cellular component unknown
 85
 ↓
 (1.8%)
 0
 ↓
 (0.0%)
 1,920 (12.8%)
     Envelope
 107
(2.2%)
 1
(0.3%)
 290 (1.9%)
     Extracellular matrix
 14
(0.3%)
 0
(0.0%)
 46 (0.3%)
     Extracellular matrix part
 4
(0.1%)
 0
(0.0%)
 23 (0.2%)
     Extracellular region
 73
 ↓
 (1.5%)
 2
(0.6%)
 416 (2.8%)
     Extracellular region part
 23
(0.5%)
 0
(0.0%)
 88 (0.6%)
     Membrane-enclosed lumen
 160
(3.3%)
 3
(0.8%)
 515 (3.4%)
     Organelle
 1,360
 ↑
 (28.1%)
 100
(27.6%)
 3,007 (20.1%)
     Organelle part
 548
(11.3%)
 22
(6.1%)
 1,632 (10.9%)
     Protein complex
 575
(11.9%)
 87
 ↑
 (24.0%)
 1,756 (11.7%)
     Synapse
 7
(0.1%)
 0
(0.0%)
 40 (0.3%)
     Synapse part
 3
(0.1%)
 0
(0.0%)
 27 (0.2%)
     Virion†
 11
 ↑
 (0.2%)
 0
(0.0%)
 1 (0.0%)
Biological process
 5,453*
(100.0%)
 630*
(100.0%)
 22,798* (100.0%)
     Biological process unknown
 61
 ↓
 (1.1%)
 0
 ↓
 (0.0%)
 888 (3.9%)
     Cellular process
 2,242
 ↑
 (41.1%)
 297
 ↑
 (47.1%)
 7,772 (34.1%)
     Development
 121
 ↓
 (2.2%)
 0
 ↓
 (0.0%)
 2,148 (9.4%)
     Growth
 17
(0.3%)
 0
(0.0%)
 102 (0.4%)
     Interaction between organisms
 6
(0.1%)
 0
(0.0%)
 92 (0.4%)
     Physiological process
 2,328
 ↑
 (42.7%)
 315
 ↑
 (50.0%)
 7,858 (34.5%)
     Pigmentation
 1
(0.0%)
 0
(0.0%)
 51 (0.2%)
     Regulation of biological process
 436
(8.0%)
 11
(1.7%)
 1,658 (7.3%)
     Reproduction
 18
 ↓
 (0.3%)
 0
 ↓
 (0.0%)
 826 (3.6%)
     Response to stimulus
 207
 ↓
 (3.8%)
 7
(1.1%)
 1,402 (6.1%)
     Viral life cycle
 16
 ↑
 (0.3%)
 0
(0.0%)
 1 (0.0%)

Listed are the numbers and percentages of assembled fire ant sequences and of D. melanogaster genes that match at least one of the second-level GO terms for molecular function, cellular component, or biological process. GO annotations for fire ant sequences were inferred electronically using two methods: blastx homology to GO-annotated proteins and Prosite protein domain scans. Statistically significant over- (↑) or underrepresentation (↓) of GO terms in fire ant relative to the Drosophila genome are indicated in bold (p < 10-8, Bonferroni-corrected hypergeometric test). *This number represents the sum of the numbers of occurences of GO terms below this level. †The 'cell part' and 'virion part' GO categories were excluded from analyses because they were redundant with the 'cell' and 'virion' categories, respectively.

Wang et al. Genome Biology 2007 8:R9   doi:10.1186/gb-2007-8-1-r9

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