Table 2

Gene Ontology annotation

Solenopsis invicta EST library

D. melanogaster genome


Blastx-determined GO

Prosite-determined GO


Molecular function

4,301*

(100.0%)

486*

(100.0%)

14,778* (100.0%)

Antioxidant activity

20

(0.5%)

2

(0.4%)

39 (0.3%)

Binding

1,765

(41.0%)

174

(35.8%)

4,319 (29.2%)

Catalytic activity

1,456

(33.9%)

201

(41.4%)

4,072 (27.6%)

Chaperone regulator activity

5

(0.1%)

0

(0.0%)

1 (0.0%)

Enzyme regulator activity

91

(2.1%)

7

(1.4%)

382 (2.6%)

Molecular function unknown

145

(3.4%)

6

(1.2%)

1,852 (12.5%)

Motor activity

29

(0.7%)

1

(0.2%)

88 (0.6%)

Nutrient reservoir activity

14

(0.3%)

0

(0.0%)

8 (0.1%)

Obsolete molecular function

0

(0.0%)

9

(1.9%)

0 (0.0%)

Signal transducer activity

153

(3.6%)

4

(0.8%)

1,091 (7.4%)

Structural molecule activity

210

(4.9%)

59

(12.1%)

759 (5.1%)

Transcription regulator activity

116

(2.7%)

4

(0.8%)

841 (5.7%)

Translation regulator activity

62

(1.4%)

7

(1.4%)

92 (0.6%)

Transporter activity

235

(5.5%)

12

(2.5%)

1,014 (6.9%)

Triplet codon-amino acid adaptor activity

0

(0.0%)

0

(0.0%)

220 (1.5%)

Cellular component

4,838*

(100.0%)

362*

(100.0%)

14,986* (100.0%)

Cell

1,868

(38.6%)

147

(40.6%)

5,225 (34.9%)

Cellular component unknown

85

(1.8%)

0

(0.0%)

1,920 (12.8%)

Envelope

107

(2.2%)

1

(0.3%)

290 (1.9%)

Extracellular matrix

14

(0.3%)

0

(0.0%)

46 (0.3%)

Extracellular matrix part

4

(0.1%)

0

(0.0%)

23 (0.2%)

Extracellular region

73

(1.5%)

2

(0.6%)

416 (2.8%)

Extracellular region part

23

(0.5%)

0

(0.0%)

88 (0.6%)

Membrane-enclosed lumen

160

(3.3%)

3

(0.8%)

515 (3.4%)

Organelle

1,360

(28.1%)

100

(27.6%)

3,007 (20.1%)

Organelle part

548

(11.3%)

22

(6.1%)

1,632 (10.9%)

Protein complex

575

(11.9%)

87

(24.0%)

1,756 (11.7%)

Synapse

7

(0.1%)

0

(0.0%)

40 (0.3%)

Synapse part

3

(0.1%)

0

(0.0%)

27 (0.2%)

Virion

11

(0.2%)

0

(0.0%)

1 (0.0%)

Biological process

5,453*

(100.0%)

630*

(100.0%)

22,798* (100.0%)

Biological process unknown

61

(1.1%)

0

(0.0%)

888 (3.9%)

Cellular process

2,242

(41.1%)

297

(47.1%)

7,772 (34.1%)

Development

121

(2.2%)

0

(0.0%)

2,148 (9.4%)

Growth

17

(0.3%)

0

(0.0%)

102 (0.4%)

Interaction between organisms

6

(0.1%)

0

(0.0%)

92 (0.4%)

Physiological process

2,328

(42.7%)

315

(50.0%)

7,858 (34.5%)

Pigmentation

1

(0.0%)

0

(0.0%)

51 (0.2%)

Regulation of biological process

436

(8.0%)

11

(1.7%)

1,658 (7.3%)

Reproduction

18

(0.3%)

0

(0.0%)

826 (3.6%)

Response to stimulus

207

(3.8%)

7

(1.1%)

1,402 (6.1%)

Viral life cycle

16

(0.3%)

0

(0.0%)

1 (0.0%)


Listed are the numbers and percentages of assembled fire ant sequences and of D. melanogaster genes that match at least one of the second-level GO terms for molecular function, cellular component, or biological process. GO annotations for fire ant sequences were inferred electronically using two methods: blastx homology to GO-annotated proteins and Prosite protein domain scans. Statistically significant over- (↑) or underrepresentation (↓) of GO terms in fire ant relative to the Drosophila genome are indicated in bold (p < 10-8, Bonferroni-corrected hypergeometric test). *This number represents the sum of the numbers of occurences of GO terms below this level. The 'cell part' and 'virion part' GO categories were excluded from analyses because they were redundant with the 'cell' and 'virion' categories, respectively.

Wang et al. Genome Biology 2007 8:R9   doi:10.1186/gb-2007-8-1-r9

Open Data