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Genes detected in the liquid association analysis shown in Figure 1 |
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| Gene ID |
Location |
Description |
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| MBP |
18q23* |
Myelin basic protein |
| PRKCA |
17q24.2* |
Protein kinase C, alpha |
| SLC1A3 |
5p13.2† |
Solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| A2M |
12p13.31* |
α2-Macroglobulin |
| GRM3 |
7q21.12 |
Glutamate receptor, metabotropic 3 |
| GFAP |
17q21.31 |
Glial fibrillary acidic protein |
| CDR1 |
Xq27.1 |
Cerebellar degeneration-related protein 1, 34kDa |
| ROM1 |
11q12.3 |
Retinal outer segment membrane protein 1 |
| CACNA1A |
19p13.2 |
Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| GRIA3 |
Xq25 |
Glutamate receptor, ionotrophic, AMPA3 |
| SOX21 |
13q32.1 |
SRY (sex determining region Y)-box 21 |
| IL7R |
5p13.2† |
Interleukin 7 receptor |
| IGHG3 |
14q32.33* |
Immunoglobulin heavy constant gamma 3 (G3m marker) |
| IGLJ3 |
22q11.1 |
Immunoglobulin lambda joining 3 |
| HLA-A |
6p21.33† |
Major histocompatibility complex, class I, A |
| HLA-B |
6p21.33† |
Major histocompatibility complex, class I, B |
| HLA-C |
6p21.33† |
Major histocompatibility complex, class I, C |
| HLA-G |
6p22.1† |
HLA-G histocompatibility antigen, class I, G |
| B2M |
15q21.1 |
β2-Microglobulin |
| PTPRC |
1q31.3* |
Protein tyrosine phosphatase, receptor type, C |
| EVI2A |
17q11.2* |
Ecotropic viral integration site 2A |
| TAP2 |
6p21.32* |
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TRIM10 |
6p21.33† |
Tripartite motif-containing 10 |
| SIAT1 |
3q27.3 |
Sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase) |
| MAG |
19q13.12* |
Myelin associated glycoprotein [M29273] |
| IRF1 |
5q23.3* |
Interferon regulatory factor 1 |
| APOE |
19q13.31* |
Apolipoprotein E |
| PDGFA |
7p22* |
Platelet-derived growth factor-α polypeptide [H89357] |
| SIAT8A |
12p12.1 |
Sialyltransferase 8A |
| SOX4 |
6p22.3† |
SRY (sex determining region Y)-box 4 |
| SOX9 |
17q24.3† |
SRY (sex determining region Y)-box 9 |
| HLA-DQB1 |
6p21.32† |
Major histocompatibility complex, class II, DQ beta 1 |
| EPHA2 |
1p36.13 |
EphA2 [T74614] |
| GMFB |
14q22.2 |
Glia maturation factor, beta |
| PDGFRA |
4q12* |
Platelet-derived growth factor receptor-α polypeptide [M21574] |
| PLP1 |
Xq22.2* |
Proteolipid protein 1 |
| KLK6 |
19q13.41 |
Kallikrein 6 (neurosin, zyme) |
| PMP2 |
8q21.13 |
Peripheral myelin protein 2 |
| CTNND2 |
5p15.2* |
Catenin delta 2 (neural plakophilin-related arm-repeat protein) |
| NTRK2 |
9q21.33 |
Neurotrophic tyrosine kinase, receptor type 2 |
| PKP4 |
2q24.1 |
Plakophilin 4 |
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*Genes previously reported associated with MS. †Genes located within the previously reported MS susceptibility loci. | ||
Li et al. Genome Biology 2007 8:R205 doi:10.1186/gb-2007-8-10-r205 |
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