Genome Biology

official impact factor 6.89

Open Access Highly Access Software

PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation

Elodie Portales-Casamar1, Stefan Kirov3,2, Jonathan Lim1, Stuart Lithwick1, Magdalena I Swanson1, Amy Ticoll1, Jay Snoddy4,2 and Wyeth W Wasserman1*

Author Affiliations

1 Centre for Molecular Medicine and Therapeutics, CFRI, University of British Columbia, Vancouver, BC., V5Z 4H4, Canada

2 Graduate School for Genome Science and Technology, Oak Ridge National Laboratory-University of Tennessee, Oak Ridge, TN, 37830, USA

3 Applied Genomics Department, Pharmaceutical Research Institute, Bristol-Myers Squibb, NJ, 08534, USA

4 Biomedical Informatics Department, Vanderbilt University School of Medicine, Nashville, TN, 37235, USA

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Genome Biology 2007, 8:R207 doi:10.1186/gb-2007-8-10-r207

Published: 28 September 2007

Abstract

PAZAR is an open-access and open-source database of transcription factor and regulatory sequence annotation with associated web interface and programming tools for data submission and extraction. Curated boutique data collections can be maintained and disseminated through the unified schema of the mall-like PAZAR repository. The Pleiades Promoter Project collection of brain-linked regulatory sequences is introduced to demonstrate the depth of annotation possible within PAZAR. PAZAR, located at http://www.pazar.info webcite, is open for business.