Genome Biology

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Open Access Research

Gene expression profiling of Hfe-/- liver and duodenum in mouse strains with differing susceptibilities to iron loading: identification of transcriptional regulatory targets of Hfe and potential hemochromatosis modifiers

Hélène Coppin1,2, Valérie Darnaud1,2, Léon Kautz1,2, Delphine Meynard1,2, Marc Aubry3,4, Jean Mosser3,4, Maria Martinez1,2 and Marie-Paule Roth1,2*

Author Affiliations

1 INSERM, U563, Centre de Physiopathologie de Toulouse Purpan, Toulouse, F-31300 France

2 Université Toulouse III Paul-Sabatier, IFR 30, Toulouse, F-31400 France

3 CNRS, UMR6061, Génétique et Développement, Rennes, F-35000 France

4 Université de Rennes 1, IFR 140, Rennes, F-35000 France

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Genome Biology 2007, 8:R221 doi:10.1186/gb-2007-8-10-r221

Published: 18 October 2007

Additional files

Additional File 1:

Presented is a table listing genes significantly regulated by Hfe disruption in the liver of D2 or B6 mice according to microarray analysis.

Format: PDF Size: 413KB Download file

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Open Data

Additional File 2:

Presented is a table listing genes significantly regulated by Hfe disruption in the duodenum of D2 or B6 mice.

Format: PDF Size: 112KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional File 3:

Presented is a table listing genes differentially expressed in the liver and/or the duodenum of wild-type D2 and B6 mice.

Format: PDF Size: 399KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data