Research
Phylogenetic simulation of promoter evolution: estimation and modeling of binding site turnover events and assessment of their impact on alignment tools
1 Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA
2 Current address: Department of Biology, Boston College, Chestnut Hill, MA 02467, USA
Genome Biology 2007, 8:R225 doi:10.1186/gb-2007-8-10-r225
Published: 24 October 2007Additional files
Additional data file 1:
Additional results of turnover simulations varying the binding site strength and GC content of the background sequences, and information on the E2F promoter data set.
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Additional data file 2:
Additional evaluations of alignment algorithms on sequence sets simulated with a phylogenetic tree with a star topology.
Format: PDF Size: 976KB Download file
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