Figure 11.

Detection accuracy of individual TFBSs on five-way mammalian alignments. All five tools perform better at detecting YY1E2F and Pax6, which have low RTRs and short restricted distance for translocation, than IRF2 and ROAZ, which have high RTR and long restricted distance for translocation. MUSCLE shows an overall better performance than the other four tools. MLAGAN performs better than DIALIGN on YY1E2F, PAX6, PPARG and ROZA, while DIALIGN shows a better performance than MLAGAN on TP53 and PPARG, which have a long restricted distance for translocation but a relatively low RTR.