Table 1 |
|
|
PSPE parameters for simulating sequence evolution |
|
| Original ancestral sequences |
Human non-coding region |
| Sequence length |
500 bp |
| Base frequencies |
A = 0.215, C = 0.287, G = 0.285, T = 0.214 |
| Substitution model |
HKY85 |
| Transition:transversion ratio |
20:1 |
| Point substitution:InDel ratio |
10:1 |
| InDel model |
Geometric distribution (p = 0.5) |
| Heterogeneity of substitution rate |
Gamma (1.0) + Iota (0.1) |
| Range of GC content |
(45%, 70%) |
| Evolution distance per step |
0.05 substitution per site |
|
|
|
|
Huang et al. Genome Biology 2007 8:R225 doi:10.1186/gb-2007-8-10-r225 |
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