Table 2

Estimated exponential rates associated with replacement turnovers of different TFBSs

TFBS

Promoter

λmean

λmedian


E2F

Simulated

0.0832

0.0724

E2F

Real

0.0833

0.0756

MycMax

Simulated

0.2200

0.2293

NFκB

Simulated

0.1032

0.0918


The probability of replacement turnover in evolution can be predicted by an exponential cumulative distribution function of divergence distance: RTR = 1 - Exp (-λ × d). λmean and λmedian are estimated rates for mean and median values, respectively.

Huang et al. Genome Biology 2007 8:R225   doi:10.1186/gb-2007-8-10-r225

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