Figure 2.

Ordered heatmap of fitted loess values. The clones on chromosome 1 are ordered along the x-axis and the HapMap samples not excluded because of the presence of chromosome-wide aberrations are plotted on the y-axis. A green/red region on the heatmap indicates that the fitted loess values in this region are consistently greater/less than zero. The samples have been ordered using the Ward agglomeration method and a Euclidean distance metric. The plot across the top of the heatmap indicates the GC content of each probe and the color bar on the right of the heatmap displays the ethnic origin of a sample: blue (YRI), yellow (CEU) and purple (CHB + JPT). The scale along the bottom gives the location of the cytobands on chromosome 1. The centromeric region is not covered by clones and has been excised from this plot, which creates the slight discontinuity at 120 Mb.