Additional data file 3.

Three panels display data from two replicate experiments: (A) Fitted loess curves for chromosome 1 (Cy3/Cy5) using dye-labeled nucleotides dCTP (purple) and dUTP (orange); (B) fitted loess curves for chromosome 1 (Cy3/Cy5) in a dye-swap experiment using dye-labeled nucleotides dCTP (purple) and dUTP (orange); (C) smoothed scatterplot of all autosomal dCTP (y-axis) vs dUTP (x-axis) loess fits for the first experiment (Cy3/Cy5); the red line is the regression line fitted to the data, which does not show a negative slope, indicating that changing the dye-labeled nucleotide does not invert the wave effect.

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Marioni et al. Genome Biology 2007 8:R228   doi:10.1186/gb-2007-8-10-r228