Table 3

Performance of the CNVmix algorithm using validated (and wave corrected) data

Calls


Status

Number of regions

A

B

C

D

E


Unvalidated

25

5

5

6

6

5

Validated

112

80

82

83

71

68

Total

137

85

87

89

77

73

False discovery rate

6

6

7

8

7

Sensitivity (confidence interval)

71 (61, 79)

73 (64, 81)

74 (65, 82)

63 (54, 72)

61 (51, 70)

Specificity (confidence interval)

80 (61, 92)

80 (61, 92)

76 (57, 90)

76 (57, 90)

80 (61, 92)


The number of regions called in five replicate experiments (A to E, ranked by standard deviation) using CNVmix with the thresholds described in the Materials and methods. The false discovery rate, sensitivity and specificity are quoted as percentages and the confidence intervals quoted are the 95% intervals.

Marioni et al. Genome Biology 2007 8:R228   doi:10.1186/gb-2007-8-10-r228

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