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Unfiltered dataset: comparison of evolutionary rates for genes in autosomes |
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| Genes in rearranged versus colinear chromosomes |
Genes in rearranged chromosomes: within versus outside inversions |
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| Colinear |
Rearranged |
P value |
Outside |
Inside |
P value |
|
|
|
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| N |
5,873 |
5,818 |
4,710 |
1,108 |
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| KI |
0.0128 |
0.0126 |
< 0.001 |
0.0128 |
0.0126 |
< 0.001 |
| KA |
0.0033 |
0.003 |
< 0.001 |
0.0031 |
0.0028 |
0.048 |
| KS |
0.0149 |
0.014 |
0.001 |
0.0146 |
0.0118 |
< 0.001 |
| KA/KI |
0.2535 |
0.2383 |
0.007 |
0.2393 |
0.2342 |
0.605 |
|
Evolutionary rates are compared for genes in colinear versus rearranged chromosomes between human and chimpanzee, and for genes in rearranged chromosomes but inside versus outside the major cytological evolutionary rearrangements between these two species. P values were calculated by means of permutation tests (1,000 random permutations). | ||||||
Marques-Bonet et al. Genome Biology 2007 8:R230 doi:10.1186/gb-2007-8-10-r230 |
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