Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Open Access Highly Accessed Research

Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster

Tatiana V Morozova123, Robert RH Anholt124 and Trudy FC Mackay24*

Author Affiliations

1 Department of Zoology, North Carolina State University, Raleigh, NC 27695, USA

2 WM Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC 27695, USA

3 Institute of Molecular Genetics RAS, Kurchatov Square, Moscow 123182, Russia

4 Department of Genetics, North Carolina State University, Raleigh, NC 27695, USA

For all author emails, please log on.

Genome Biology 2007, 8:R231  doi:10.1186/gb-2007-8-10-r231

Published: 31 October 2007

Additional files

Additional data file 1:

Probe sets differentially expressed between selection lines at q < 0.001.

Format: XLS Size: 1MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 2:

Probe sets with significant differences in contrast statements at p < 0.05.

Format: XLS Size: 874KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 3:

The 121 probe sets with larger than two-fold differences in transcript abundance between selection lines.

Format: XLS Size: 115KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 4:

Biological processes GO categories of genes in Additional data file 3.

Format: XLS Size: 209KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 5:

Biological processes GO categories of genes in Additional data file 2.

Format: XLS Size: 2.6MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 6:

Molecular function GO categories of genes in Additional data file 2.

Format: XLS Size: 1.4MB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 7:

Common probe sets of differentially expressed genes from three artificially selected populations.

Format: XLS Size: 90KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 8:

Biological processes GO categories of genes in Additional data file 7.

Format: XLS Size: 63KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 9:

Common probe sets differentially expressed in response to exposure to ethanol in two experiments (artificial selection for alcohol sensitivity/resistant and tolerance development).

Format: XLS Size: 69KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 10:

Genes previously implicated in alcohol sensitivity in Drosophila melanogaster.

Format: DOC Size: 275KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional data file 11:

Drosophila probe sets of genes with human orthologues differentially expressed in alcoholics' brain regions.

Format: XLS Size: 26KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional data file 12:

Drosophila probe sets of genes that are differentially expressed in response to artificial selection and have murine orthologues associated with alcohol related phenotypes.

Format: XLS Size: 130KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data