Research
Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster
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* Corresponding author: Trudy FC Mackay trudy_mackay@ncsu.edu
1 Department of Zoology, North Carolina State University, Raleigh, NC 27695, USA
2 WM Keck Center for Behavioral Biology, North Carolina State University, Raleigh, NC 27695, USA
3 Institute of Molecular Genetics RAS, Kurchatov Square, Moscow 123182, Russia
4 Department of Genetics, North Carolina State University, Raleigh, NC 27695, USA
Genome Biology 2007, 8:R231 doi:10.1186/gb-2007-8-10-r231
Published: 31 October 2007Additional files
Additional data file 1:
Probe sets differentially expressed between selection lines at q < 0.001.
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Additional data file 2:
Probe sets with significant differences in contrast statements at p < 0.05.
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Additional data file 3:
The 121 probe sets with larger than two-fold differences in transcript abundance between selection lines.
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Additional data file 4:
Biological processes GO categories of genes in Additional data file 3.
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Additional data file 5:
Biological processes GO categories of genes in Additional data file 2.
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Additional data file 6:
Molecular function GO categories of genes in Additional data file 2.
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Additional data file 7:
Common probe sets of differentially expressed genes from three artificially selected populations.
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Additional data file 8:
Biological processes GO categories of genes in Additional data file 7.
Format: XLS Size: 63KB Download file
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Additional data file 9:
Common probe sets differentially expressed in response to exposure to ethanol in two experiments (artificial selection for alcohol sensitivity/resistant and tolerance development).
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Additional data file 10:
Genes previously implicated in alcohol sensitivity in Drosophila melanogaster.
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Additional data file 11:
Drosophila probe sets of genes with human orthologues differentially expressed in alcoholics' brain regions.
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Additional data file 12:
Drosophila probe sets of genes that are differentially expressed in response to artificial selection and have murine orthologues associated with alcohol related phenotypes.
Format: XLS Size: 130KB Download file
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