Table 1

G1/S genes that are co-regulated during spore germination

Gene

Description

Genes expressed early in germination (genes 1-13 in Figure 10)

YBL009W

Protein of unknown function

RDH54

Protein required for mitotic diploid-specific recombination and repair and for meiosis

HCM1

Dosage-dependent suppressor of cmd1 and member of the forkhead family of DNA-binding proteins

SHO1

Osmosensor in the HOG1 MAP kinase, high-osmolarity signal transduction pathway, has an SH3 domain

YGR151C

Protein of unknown function

RSR1

GTP-binding protein involved in bud site selection, member of the ras family in the ras superfamily

YKL089W

Centromere protein required for normal chromosome segregation and spindle integrity

SPH1

Protein involved in polarized growth, with roles in shmoo formation and bud site selection

OGG1

DNA glycosylase, excises 7,8-dihydro-8-oxoguanine (8-OxoG) and formamidopyrimidine (Fapy) residues from DNA

BNI5

Protein of unknown function, localizes to the mother-bud neck

BNI4

Protein that may be involved in linking chitin synthase III to septins of the neck filaments

EXO1

Double-stranded DNA 5'→3' exonuclease, involved in mismatch repair and recombination

BBP1

Protein of the spindle pole body that binds to Bfr1p

Genes expressed late in germination (genes 81-98 in Figure 10)

RFA1

DNA replication factor A, 69K subunit, binds single-stranded DNA

HTA2

Histone H2A, nearly identical to Hta1p

POL30

Proliferating cell nuclear antigen (PCNA), required for DNA synthesis and DNA repair

MCD1

Cohesin, protein required for mitotic chromatid cohesion and chromosome condensation

HTA1

Histone H2A, nearly identical to Hta2p

RNR1

Ribonucleotide reductase (ribonucleoside-diphosphate reductase) large subunit, converts ribonucleoside diphosphate to deoxyribonucleoside diphosphate

RFA3

DNA replication factor A, 13K subunit

YLR049C

Protein of unknown function

TOS4

Protein of unknown function

YOX1

Protein with a homeodomain that binds tRNA-Leu gene

CTF18

Protein required for accurate chromosome transmission in mitosis and maintenance of normal telomere length homolog of Rfc1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p

HHF2

Histone H4, identical to Hhf1p

RFA2

DNA replication factor A, 36K subunit phosphorylated at the G1/S transition and dephosphorylated at mitosis

YNR009W

Protein of unknown function

CSI2

Protein involved in chitin synthesis

MSH2

Component with Msh3p and Msh6p of DNA mismatch binding factor, involved in repair of single base mismatches and short insertions/deletions

CDC21

Thymidylate synthase, catalyzes the reductive methylation of dUMP by 5,10-methylene-5,6,7,8-tetrahydrofolate to produce dTMP and 7,8-dihydrofolate

HHO1

Histone H1

Joseph-Strauss et al. Genome Biology 2007 8:R241   doi:10.1186/gb-2007-8-11-r241