Genome Biology

official impact factor 6.89

Open Access Research

Quantification of ortholog losses in insects and vertebrates

Stefan Wyder1,2, Evgenia V Kriventseva3,2, Reinhard Schröder4, Tatsuhiko Kadowaki5 and Evgeny M Zdobnov1,2,6*

Author Affiliations

1 Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland

2 Swiss Institute of Bioinformatics, rue Michel-Servet, 1211 Geneva, Switzerland

3 Department of Structural Biology and Bioinformatics, University of Geneva Medical School, rue Michel-Servet, 1211 Geneva, Switzerland

4 Interf. Institut für Zellbiologie, Abt. Genetik der Tiere, Universität Tübingen, 72076 Tübingen, Germany

5 Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa, Nagoya 464-8601, Japan

6 Imperial College London, South Kensington Campus, London SW7 2AZ, UK

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Genome Biology 2007, 8:R242 doi:10.1186/gb-2007-8-11-r242

Published: 16 November 2007

Additional files

Additional data File 1:

Correlation between the absolute number of lost orthologous groups and the rate of amino acid substitutions.

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Open Data

Additional data File 2:

Phylogenetic analysis of SID-1 proteins.

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Additional data File 3:

Phylogenetic analysis of CDC7 proteins.

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Additional data File 4:

GO analysis of insect-specific orthologous groups lost in all Dipterans.

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Open Data

Additional data File 5:

Coeliminiation of functionally linked genes in the Diptera and Drosophila lineages.

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Additional data File 6:

Phylogenetic analysis of Fboxo7, cdk4 and cyclin D.

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Additional data File 7:

Alignment of Fboxo7 proteins.

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Open Data