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Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa

Carol J Loscher* 1 email, Karsten Hokamp1 email, Paul F Kenna1 email, Alasdair C Ivens2 email, Peter Humphries1 email, Arpad Palfi* 1 email and G Jane Farrar1 email

1Smurfit Institute of Genetics, Trinity College Dublin, College Green, Dublin 2, Ireland

2Wellcome Trust Genome Campus, Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK

author email corresponding author email* Contributed equally

Genome Biology 2007, 8:R248doi:10.1186/gb-2007-8-11-r248

Published: 22 November 2007

Subject areas: Medicine, Physiology, Genome studies


Additional files

Additional data file 1:

Log2 median ratios are given for c57, 129, and P347S retinas at age 1 month; analysis was carried out in triplicate. P values by Student's t-test are also provided.

Format: XLS Size: 494KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional data file 2:

Global normalised log2 ratios are given for c57, 129, and P347S retinas at age 1 month; analysis was carried out in triplicate. P values by analysis of variance and Student's t-test are also provided.

Format: XLS Size: 211KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional data file 3:

Presented is a table listing highly ranked retinal miR target genes predicted using miRanda.

Format: XLS Size: 24KB Download file

This file can be viewed with: Microsoft Excel Viewer


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