Genome Biology

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Using protein complexes to predict phenotypic effects of gene mutation

Hunter B Fraser1* and Joshua B Plotkin2

Author Affiliations

1 Broad Institute of Harvard and MIT, 320 Charles St, Cambridge, Massachhusetts 02142, USA

2 Department of Biology, University of Pennsylvania, 433 S. University Ave, Philadelphia, Pennsylvania 19104, USA

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Genome Biology 2007, 8:R252 doi:10.1186/gb-2007-8-11-r252

Published: 27 November 2007

Additional files

Additional data file 1:

Presented is a table listing the top 92 predictions of gene pairs most likely to cause the same disease, as assessed by physical interaction in the HPRD database and co-expression.

Format: TXT Size: 4KB Download file

Open Data