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Using protein complexes to predict phenotypic effects of gene mutation

Hunter B Fraser1 email and Joshua B Plotkin2 email

1Broad Institute of Harvard and MIT, 320 Charles St, Cambridge, Massachhusetts 02142, USA

2Department of Biology, University of Pennsylvania, 433 S. University Ave, Philadelphia, Pennsylvania 19104, USA

author email corresponding author email

Genome Biology 2007, 8:R252doi:10.1186/gb-2007-8-11-r252

Published: 27 November 2007

Subject areas: Bioinformatics, Genetics, Medicine


Additional files

Additional data file 1:

Presented is a table listing the top 92 predictions of gene pairs most likely to cause the same disease, as assessed by physical interaction in the HPRD database and co-expression.

Format: TXT Size: 4KB Download file


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