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Review

Building on basic metagenomics with complementary technologies

Falk Warnecke and Philip Hugenholtz email

Microbial Ecology Program, DOE Joint Genome Institute, Walnut Creek, CA 94598, USA

author email corresponding author email

Genome Biology 2007, 8:231doi:10.1186/gb-2007-8-12-231

Published: 28 December 2007

Subject areas: Ecology, Genome studies, Methods, Microbiology and parasitology

Abstract

Metagenomics, the application of random shotgun sequencing to environmental samples, is a powerful approach for characterizing microbial communities. However, this method only represents the cornerstone of what can be achieved using a range of complementary technologies such as transcriptomics, proteomics, cell sorting and microfluidics. Together, these approaches hold great promise for the study of microbial ecology and evolution.


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