Genome Biology
Volume 8
Issue 12 |
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MinireviewGene prediction: compare and CONTRASTPaul Flicek  European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK  author email corresponding author email
Genome Biology 2007,
8:233doi:10.1186/gb-2007-8-12-233
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| Published: |
20 December 2007 |
Subject areas: Bioinformatics, Methods, Genome studies Abstract
CONTRAST, a new gene-prediction algorithm that uses sophisticated machine-learning techniques, has pushed de novo prediction accuracy to new heights, and has significantly closed the gap between de novo and evidence-based methods for human genome annotation. | 
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