Table 1

Set of known human multi-protein complexes analyzed



Number of genes



Protein complex
Complex type
Thy-Thy2
Thy-Thy3
Thy-Noc

ATP_F0
Permanent
7
10
10
ATP_F1
Permanent
4
3
3
COX
Permanent
7
6
8
SRS
Permanent
16
20
20
LRS
Permanent
15
18
18
MLRS
Permanent
22
36
37
MSRS
Permanent
20
30
30
Proteasome
Permanent
21
21
23
PD
Permanent
6
7
7
RNA Pol II
Permanent
10
10
10
RNA Pol III
Permanent
4
6
5
AP2
Transient
2
4
4
APC
Transient
5
8
8
Arp2-3
Transient
6
3
5
ARC
Transient
4
5
5
Centrosome
Transient
42
50
51
Dynactin
Transient
7
9
7
Exocyst
Transient
7
7
7
Exosome
Transient
3
5
5
FA
Transient
37
46
47
GTC
Transient
5
6
6
Nucleopore
Transient
27
29
30
Nucleosome
Transient
17
24
24
ORC
Transient
4
5
6
RFC
Transient
3
4
4
SRP
Transient
3
5
4
SCF
Transient
3
3
3
SNARE complex
Transient
7
7
7
SWI-SNF
Transient
12
10
12
TAFIID
Transient
8
13
13
TRAPP
Transient
2
5
6
VHL
Transient
4
4
4

The number of genes representing each protein complex is reported for the three analyzed HeLa cell-cycle datasets. AP2, adaptor-related protein complex 2; APC, anaphase promoting complex; ARC, axin related complex; ATP_F0, ATP synthase, H+ transporting, mitochondrial F0 complex; ATP_F1, ATP synthase, H+ transporting, mitochondrial F1 complex; COX, cytochrome c oxidase; FA, focal adhesion; GTC, golgi transport complex; MSRS, mitochondrial small ribosomal subunit; ORC, origin recognition complex; PD, pyruvate dehydrogenase; RNA Pol II, RNA polymerase II; SRP, signal recognition particle; TRAPP, trafficking protein particle complex; VHL, von Hippel-Lindau complex.

Zanivan et al. Genome Biology 2007 8:R256   doi:10.1186/gb-2007-8-12-r256