Table 1

Mechanisms of ITS insertion

Number of loci


Rodents
 Primates

Flanking sequence modification
 Mouse
 Rat
 Total (%)
 Human
 Chimp
 Both*
 Total (%)
No modification
 15
 16
 31 (23,2)
 1
 0
 3
 4 (16)
Deletion
 27
 38
 65 (50)
 2
 2
 9
 13 (52)
Addition
 10
 12
 22 (17)
 1
 1
 2
 4 (16)
     Random sequence
 8
 12




     TERC sequence†
 2
 0




Duplication
 2
 4
 6 (4,6)
 1
 1
 2
 4 (16)
Addition and deletion
 4
 2
 6 (4,6)
 0
 0
 0
 0 (0)
     Random sequence addition
 1
 2




     TERC sequence addition†
 3
 0




Total
 58
 72
 130 (100)
 5
 4
 16
 25 (100)

*These ITSs are present in both primate species and were inserted within repetitive elements. Their insertion mechanism was defined from the repetitive element consensus. †TERC sequence additions are present only in rodents.

Nergadze et al. Genome Biology 2007 8:R260   doi:10.1186/gb-2007-8-12-r260

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