Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes
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* Corresponding author: John Tower jtower@usc.edu
Genome Biology 2007, 8:R262 doi:10.1186/gb-2007-8-12-r262
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Sergey V Nuzhdin, Jennifer A Brisson, Andrew Pickering, Marta L Wayne, Lawrence G Harshman, Lauren M McIntyre BMC Genomics 2009, 10:124 (24 March 2009) Naturally-occurring variation in Drosophila insulin/TOR signaling pathway genes affects expression and phenotypes similarly to gene knockouts, but the sparse picture of regulatory networks derived from knockout studies on inbred lines is probably oversimplified.
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