Determining promoter location based on DNA structure first-principles calculations

J Ramon Goñi¹^,2^,3 , Alberto Pérez¹^,2 , David Torrents⁴^,5 and Modesto Orozco¹^,4^,6

¹Institute for Research in Biomedicine, Parc Científic de Barcelona, Josep Samitier, Barcelona 08028, Spain

²Departament de Bioquímica i Biología Molecular, Facultat de Biología, Avgda Diagonal, Barcelona 08028, Spain

³Grup de recerca en Bioinformàtica i Estadística Mèdica, Departament de Biologia de Sistemes, Universitat de Vic. Laura, 13 08500 VIC, Spain

⁴Computational Biology Program, Barcelona Supercomputer Center, Jordi Girona, Edifici Torre Girona, Barcelona 08028, Spain

⁵Institut Català per la Recerca i Estudis Avançats (ICREA), Passeig Lluís Companys, 23. Barcelona 08010, Spain

⁶Instituto Nacional de Bioinformática, Structural Bioinformatics Unit, Parc Cientific de Barcelona, Josep Samitier, Barcelona 08028, USA

author email corresponding author email

Genome Biology 2007, 8:R263doi:10.1186/gb-2007-8-12-r263


Published:	11 December 2007

Subject areas: Biochemistry and structural biology, Bioinformatics, Methods

Additional file 1:

Supplementary figures showing plots of dinucleotide helical parameters and additional performance tests of ProStar.

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Additional file 2:

Promoter prediction methods described in this paper and a detailed evaluation of their performance.

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Additional file 3:

Extended description of the performance test and the averaged score measure.

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