Genome Biology

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Characterization of probiotic Escherichia coli isolates with a novel pan-genome microarray

Hanni Willenbrock*, Peter F Hallin, Trudy M Wassenaar and David W Ussery

Genome Biology 2007, 8:R267 doi:10.1186/gb-2007-8-12-r267

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Analysis of intra-genomic GC content homogeneity within prokaryotes

Jon Bohlin, Lars Snipen, Simon P Hardy, Anja B Kristoffersen, Karin Lagesen, Torunn Dønsvik, Eystein Skjerve, David W Ussery BMC Genomics 2010, 11:464 (6 August 2010)

Methodology article   Open Access Highly Accessed

Microbial comparative pan-genomics using binomial mixture models

Lars Snipen, Trygve Almøy, David W Ussery BMC Genomics 2009, 10:385 (19 August 2009)

Pan-genomes encompass all genes found within a given taxa, and a new approach to estimating their size, applied to 16 bacterial species, gives results ranging from around 2600 gene families in Buchnera aphidicola to around 43000 in Escherichia coli.