Table 4

Performance on the EGASP test regions. Sensitivity (Sn) and specificity (Sp) are shown at the nucleotide (Nuc), exon, transcript (Trans) and gene levels for CONTRAST and the 19 predictors entered in the EGASP experiment. At each level of evaluation, the performance of the predictor with the highest average sensitivity and specificity for a given category is shown in bold. Also shown is the performance of the UCSC RefGene track, which consists of RefSeq cDNAs aligned to the genome. The track was evaluated just before the start of the EGASP workshop.


Nuc Sn
Nuc Sp
Exon Sn
Exon Sp
Trans Sn
Trans Sp
Gene Sn
Gene Sp

RefGene Track
85.34
98.50
73.23
94.67
41.91
75.21
77.03
82.56









Category 1 (any information)
AUGUSTUS-any
94.42
82.43
74.67
76.76
22.65
35.59
47.97
35.59
FGENESH++
91.09
76.89
75.18
69.31
36.21
41.61
69.93
42.09
JIGSAW
94.56
92.19
80.61
89.33
34.05
65.95
72.64
65.95
PAIRAGON-any
87.77
92.78
76.85
88.91
39.29
60.34
69.59
61.32









Category 2 (target sequence)
AUGUSTUS-abinit
78.65
75.29
52.39
62.93
11.09
17.22
24.32
17.22
GENEMARK.hmm-A
78.43
37.97
50.58
29.01
6.93
3.24
15.20
3.24
GENEMARK.hmm-B
76.09
62.94
48.15
47.25
7.70
7.91
16.89
7.91
GENEZILLA
87.56
50.93
62.08
50.25
9.09
8.84
19.59
8.84









Category 3 (protein, mRNA, EST)
ACEVIEW
90.94
79.14
85.75
56.98
44.68
19.31
63.51
48.65
AUGUSTUS-EST
92.62
83.45
74.10
77.40
22.50
37.01
47.64
37.01
ENSEMBL
90.18
92.02
77.53
82.65
39.75
54.64
71.62
67.32
EXOGEAN
84.18
94.33
79.34
83.45
42.53
52.44
63.18
80.82
EXONHUNTER
90.46
59.67
64.44
41.77
10.48
6.33
21.96
6.33
PAIRAGON+NSCAN_EST
87.56
92.77
76.63
88.95
39.29
60.64
69.59
61.71









Category 4 (genomic alignments)
CONTRAST
94.44
89.25
77.68
86.02
25.12
47.87
53.04
47.87
AUGUSTUS-dual
88.86
80.15
63.06
69.14
12.33
18.64
26.01
18.64
DOGFISH
64.81
88.24
53.11
77.34
5.08
14.61
10.81
14.61
MARS
84.25
74.13
65.56
61.65
15.87
15.11
33.45
24.94
NSCAN
85.38
89.02
67.66
82.05
16.95
36.71
35.47
36.71
SAGA
52.54
81.39
38.82
50.73
2.16
3.44
4.39
3.44

Gross et al. Genome Biology 2007 8:R269   doi:10.1186/gb-2007-8-12-r269

Open Data