Table 4 |
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|
Performance on the EGASP test regions. Sensitivity (Sn) and specificity (Sp) are shown at the nucleotide (Nuc), exon, transcript (Trans) and gene levels for CONTRAST and the 19 predictors entered in the EGASP experiment. At each level of evaluation, the performance of the predictor with the highest average sensitivity and specificity for a given category is shown in bold. Also shown is the performance of the UCSC RefGene track, which consists of RefSeq cDNAs aligned to the genome. The track was evaluated just before the start of the EGASP workshop. |
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| Nuc Sn |
Nuc Sp |
Exon Sn |
Exon Sp |
Trans Sn |
Trans Sp |
Gene Sn |
Gene Sp |
|
|
|
||||||||
| RefGene Track |
85.34 |
98.50 |
73.23 |
94.67 |
41.91 |
75.21 |
77.03 |
82.56 |
| Category 1 (any information) |
||||||||
| AUGUSTUS-any |
94.42 |
82.43 |
74.67 |
76.76 |
22.65 |
35.59 |
47.97 |
35.59 |
| FGENESH++ |
91.09 |
76.89 |
75.18 |
69.31 |
36.21 |
41.61 |
69.93 |
42.09 |
| JIGSAW |
94.56 |
92.19 |
80.61 |
89.33 |
34.05 |
65.95 |
72.64 |
65.95 |
| PAIRAGON-any |
87.77 |
92.78 |
76.85 |
88.91 |
39.29 |
60.34 |
69.59 |
61.32 |
| Category 2 (target sequence) |
||||||||
| AUGUSTUS-abinit |
78.65 |
75.29 |
52.39 |
62.93 |
11.09 |
17.22 |
24.32 |
17.22 |
| GENEMARK.hmm-A |
78.43 |
37.97 |
50.58 |
29.01 |
6.93 |
3.24 |
15.20 |
3.24 |
| GENEMARK.hmm-B |
76.09 |
62.94 |
48.15 |
47.25 |
7.70 |
7.91 |
16.89 |
7.91 |
| GENEZILLA |
87.56 |
50.93 |
62.08 |
50.25 |
9.09 |
8.84 |
19.59 |
8.84 |
| Category 3 (protein, mRNA, EST) |
||||||||
| ACEVIEW |
90.94 |
79.14 |
85.75 |
56.98 |
44.68 |
19.31 |
63.51 |
48.65 |
| AUGUSTUS-EST |
92.62 |
83.45 |
74.10 |
77.40 |
22.50 |
37.01 |
47.64 |
37.01 |
| ENSEMBL |
90.18 |
92.02 |
77.53 |
82.65 |
39.75 |
54.64 |
71.62 |
67.32 |
| EXOGEAN |
84.18 |
94.33 |
79.34 |
83.45 |
42.53 |
52.44 |
63.18 |
80.82 |
| EXONHUNTER |
90.46 |
59.67 |
64.44 |
41.77 |
10.48 |
6.33 |
21.96 |
6.33 |
| PAIRAGON+NSCAN_EST |
87.56 |
92.77 |
76.63 |
88.95 |
39.29 |
60.64 |
69.59 |
61.71 |
| Category 4 (genomic alignments) |
||||||||
| CONTRAST |
94.44 |
89.25 |
77.68 |
86.02 |
25.12 |
47.87 |
53.04 |
47.87 |
| AUGUSTUS-dual |
88.86 |
80.15 |
63.06 |
69.14 |
12.33 |
18.64 |
26.01 |
18.64 |
| DOGFISH |
64.81 |
88.24 |
53.11 |
77.34 |
5.08 |
14.61 |
10.81 |
14.61 |
| MARS |
84.25 |
74.13 |
65.56 |
61.65 |
15.87 |
15.11 |
33.45 |
24.94 |
| NSCAN |
85.38 |
89.02 |
67.66 |
82.05 |
16.95 |
36.71 |
35.47 |
36.71 |
| SAGA |
52.54 |
81.39 |
38.82 |
50.73 |
2.16 |
3.44 |
4.39 |
3.44 |
|
|
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|
Gross et al. Genome Biology 2007 8:R269 doi:10.1186/gb-2007-8-12-r269 |
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