Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Comment

And the second shall be first

Gregory A Petsko

Author Affiliations

Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA 02454-9110, USA

Genome Biology 2007, 8:103  doi:10.1186/gb-2007-8-2-103

Published: 26 February 2007

The retraction of 5 protein crystal structures has held back an entire sub-field for years due to the inordinately persuasive power of the pretty pictures that structural biology produces. All too often the first report is sketchy, superficial in its analysis, and prone to error. The second report is often more thoughtful, more useful, and is essential to the scientific process of validation and self-correction.