Decoding dosage compensation
Department of Pathology, University of Washington, Seattle, WA 98195, USA
Genome Biology 2007, 8:204 doi:10.1186/gb-2007-8-2-204Published: 26 February 2007
How the mechanisms of dosage compensation distinguish the sex chromosomes from the autosomes has been something of a mystery. A recent study in Caenorhabditis elegans has identified clusters of two common DNA motifs as a cis-acting code for the recruitment of the DCC, the protein complex that mediates dosage compensation.