Genome Biology

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Patterns and rates of intron divergence between humans and chimpanzees

Elodie Gazave1, Tomàs Marqués-Bonet1, Olga Fernando1,2, Brian Charlesworth3 and Arcadi Navarro4*

Author Affiliations

1 Unitat de Biologia Evolutiva, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Carrer Dr Aiguader 88, 08003 Barcelona, Catalonia, Spain

2 Instituto de Tecnologia Química e Biológica (ITQB), Universidade Nova de Lisboa, Av. da República (EAN) 2781-901 Oeiras, Lisboa, Portugal

3 Institute of Evolutionary Biology, University of Edinburgh, West Mains Road, Edinburgh, Scotland, EH7 3JT, UK

4 Institucio Catalana de Recerca i Estudis Avancats (ICREA), Unitat de Biologia Evolutiva, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Carrer Dr Aiguader 88, 08003 Barcelona, Catalonia, Spain

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Genome Biology 2007, 8:R21 doi:10.1186/gb-2007-8-2-r21

Published: 19 February 2007

Additional files

Additional data file 1:

A table listing the mean Ki and mean lengths for the main known factors affecting divergence rates.

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Additional data file 2:

A figure representing the mean GC content and mean Ki for short and long introns.

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Additional data file 3:

Comparative distribution of intron length between human and Drosophila.

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Additional data file 4:

Human RefSeq of the introns included in the analysis, with the main factors and variables we study here: Ki, GC, first, and length (lengths are given for the sequences after masking).

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