Genome Biology

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DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies

Iiris Hovatta, Matthew A Zapala, Ron S Broide, Eric E Schadt, Ondrej Libiger, Nicholas J Schork, David J Lockhart and Carrolee Barlow*

Genome Biology 2007, 8:R25 doi:10.1186/gb-2007-8-2-r25

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Research article   Open Access

Genotype and expression analysis of two inbred mouse strains and two derived congenic strains suggest that most gene expression is trans regulated and sensitive to genetic background

Harry A Noyes, Morris Agaba, Susan Anderson, Alan L Archibald, Andy Brass, John Gibson, Laurence Hall, Helen Hulme, Sung Oh, Stephen Kemp BMC Genomics 2010, 11:361 (7 June 2010)

Research article   Open Access

Gene expression profiling in C57BL/6J and A/J mouse inbred strains reveals gene networks specific for brain regions independent of genetic background

Simone de Jong, Tova F Fuller, Esther Janson, Eric Strengman, Steve Horvath, Martien JH Kas, Roel A Ophoff BMC Genomics 2010, 11:20 (11 January 2010)

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Promoter architecture and the evolvability of gene expression

Itay Tirosh, Naama Barkai, Kevin J Verstrepen Journal of Biology 2009, 8:95 (14 December 2009)

Major evolutionary change depends on changes in gene expression. Itay Tirosh and colleagues review recent research on the influence of promoter architecture and mutations in regulatory proteins on divergent expression patterns and suggest what is required for evolvability.

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Correlational analysis for identifying genes whose regulation contributes to chronic neuropathic pain

Anna-Karin Persson, Mathias Gebauer, Suzana Jordan, Christiane Metz-Weidmann, Anke M Schulte, Hans-Christoph Schneider, Danping Ding-Pfennigdorff, Jonas Thun, Xiao-Jun Xu, Zsuzsanna Wiesenfeld-Hallin, Ariel Darvasi, Kaj Fried, Marshall Devor Molecular Pain 2009, 5:7 (19 February 2009)

Research   Open Access

Morphine effects on striatal transcriptome in mice

Michal Korostynski, Marcin Piechota, Dorota Kaminska, Wojciech Solecki, Ryszard Przewlocki Genome Biology 2007, 8:R128 (28 June 2007)

Global transcriptional analysis of mouse striata following acute and chronic exposure to morphine reveals multiple physiological factors which may affect opioid-related phenotypes and implicates a number of gene networks, including glucocorticoid receptor regulated genes, in the response to this opioid.