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Hox go omics: insights from Drosophila into Hox gene targets

Anastasios Pavlopoulos* and Michael Akam

Author Affiliations

Laboratory for Development and Evolution, University Museum of Zoology, Department of Zoology, Downing Street, Cambridge CB2 3EJ, UK

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Genome Biology 2007, 8:208  doi:10.1186/gb-2007-8-3-208

Published: 29 March 2007

Abstract

Genetic studies of the targets of the Hox genes have revealed only the tip of the iceberg. Recent microarray studies that have identified hundreds more transcriptional responses to Hox genes in Drosophila will help elucidate the role of Hox genes in development and evolution.