The genome of Apis mellifera: dialog between linkage mapping and sequence assembly
1 Laboratoire Evolution, Génomes et Spéciation, Centre National de la Recherche Scientifique, 91198 Gif-sur-Yvette cedex, France and University of Paris Sud, 91405 Orsay, France
2 Human Genome Sequencing Center, Baylor College of Medicine, Alkek 1519, One Baylor Plaza, Houston, TX 77030, USA
3 Centre de Biologie et de Gestion des Populations, INRA, CS 30016 Montferrier-sur-Lez, 34988 Saint-Gélydu-Fesc, France
Genome Biology 2007, 8:403 doi:10.1186/gb-2007-8-3-403Published: 19 March 2007
Two independent genome projects for the honey bee, a microsatellite linkage map and a genome sequence assembly, interactively produced an almost complete organization of the euchromatic genome. Assembly 4.0 now includes 626 scaffolds that were ordered and oriented into chromosomes according to the framework provided by the third-generation linkage map (AmelMap3). Each construct was used to control the quality of the other. The co-linearity of markers in the sequence and the map is almost perfect and argues in favor of the high quality of both.