Genome Biology

official impact factor 6.89

Open Access Research

Developmental stage related patterns of codon usage and genomic GC content: searching for evolutionary fingerprints with models of stem cell differentiation

Lichen Ren1, Ge Gao2, Dongxin Zhao3, Mingxiao Ding3, Jingchu Luo2 and Hongkui Deng3*

Author Affiliations

1 College of Life Sciences, Shanghai Jiao Tong University, Shanghai, 200240, PR China

2 Center for Bioinformatics, College of Life Sciences, National Laboratory of Protein Engineering and Plant Genetics Engineering, Peking University, Beijing, 100871, PR China

3 Department of Cell Biology and Genetics, College of Life Sciences, Peking University, Beijing, 100871, PR China

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Genome Biology 2007, 8:R35 doi:10.1186/gb-2007-8-3-r35

Published: 12 March 2007

Additional files

Additional data file 1:

Comparisons of GC3 and GCg between developmental-pivotal genes and developmental-specific genes

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Additional data file 2:

Levels of gene expression are correlated with codon usage, recombination rate, gene length and nucleotide composition

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Additional data file 3:

Fold changes of gene expression are correlated with codon usage, recombination rate and gene length

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Additional data file 4:

GC3 and GCg of developmental-pivotal genes, developmental-specific genes and both together in each differentiation pair

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Additional data file 5:

Comparisons of substitution rates between developmental-pivotal genes and developmental-specific genes

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Open Data