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Descriptions and definitions of each cell type in the models of stem cell differentiation |
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| Abbreviation |
Model |
Descriptions |
Definitions |
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| ESC |
A |
Pluripotent stem cell |
C57Bl/6 cell line |
| NSC |
A |
Adult neural stem cell |
*Neurosphere |
| LVB |
A |
Adult mature neural cell |
Lateral ventricles of the brain |
| HSC |
A |
Long-term hematopoietic stem cell |
†Lin- c-Kit+ Sca-1+ CD34- Hoelow |
| BM |
A |
Non-hematopoietic stem cell |
Bone marrow main population |
| ESC |
B |
Pluripotent stem cell |
CCE cell line |
| FNSC |
B |
Fetal neural stem cell |
*†Hoelow from neurosphere |
| FLHSC |
B |
Fetal liver hematopoietic stem cell |
†Lin- AA4.1+ c-Kit+ Sca-1+ |
| FLLCP |
B |
Fetal liver hematopoietic progenitor cell |
†Lin- AA4.1+ c-Kit+ Sca-1- |
| FLMBC |
B |
Fetal liver mature blood cell |
†Lin+ |
| LTHSC |
B |
Long-term hematopoietic stem cell |
†Lin- c-Kit+ Sca-1+Rholow |
| STHSC |
B |
Short-term hematopoietic stem cell |
†Lin-c-Kit+ Sca-1+Rhohigh |
| LCP |
B |
Hematopoietic progenitor cell |
†Lin-c-Kit+ Sca-1- |
| MBC |
B |
Mature blood cell |
†Lin+ |
| CD45 |
B |
Contain long-term hematopoietic stem cells |
†CD45+ c-Kit+ Sca-1+ |
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Stem cells and progenitor cells are defined in terms of their surface markers (†by FACS sorting) and/or growth characters (*by selective culture). ESCs in both models A and B were functionally tested. For detailed descriptions and related references, see [54,55]. | |||
Ren et al. Genome Biology 2007 8:R35 doi:10.1186/gb-2007-8-3-r35 |
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