Gene phylogeny was explored using a sequential blast pipeline. (a) All known mouse proteins were sequentially blasted (cutoff value E = 10-4) against available databases and then classified according to their appearance into seven different categories: prokaryota (pro), eukaryota (euk), metazoa (met), deuterostomia (deu), chordata (cor), vertebrata (ver), and mammalia (mam). (b) The table shows the number of mouse genes assigned to each category compared with their estimated age in millions of years. (c) Graphical representation of the global gene phylogeny.
Martinez-Morales et al. Genome Biology 2007 8:R36 doi:10.1186/gb-2007-8-3-r36