Table 2

Neural crest genes compiled using Phenotype Ontology annotations (phenotypic information derived from mutant mice studies)

Group

Gene


Deuterostomia

Brain derived neurotrophic factor

Fanconi anemia, complementation group A

Fos-like antigen 2

Neurotropin 3

Noggin

Purinergic receptor P2X, ligand-gated ion channel, 7

Rod outer segment membrane protein 1


Vertebrata

BCL2-like 11 (apoptosis facilitator)

Calcitonin/calcitonin-related polypeptide, alpha

Cocaine and amphetamine regulated transcript

Endothelin 1

Endothelin 3

Formin 1

Glial cell line derived neurotrophic factor

Gonadotropin releasing hormone 1

Hermansky-Pudlak syndrome 6

Integrin, alpha 10

Islet amyloid polypeptide

Leukocyte cell derived chemotaxin 1

Matrix Gla protein

Melanoma inhibitory activity 1

Myelin protein zero

Natriuretic peptide precursor type C

Neuregulin 1

Neurturin

Parathyroid hormone

Parathyroid hormone-like peptide

Phosphodiesterase 6G, cGMP-specific, rod, gamma

Pro-opiomelanocortin-alpha

Silver

Tenomodulin

Treacher Collins Franceschetti syndrome 1, homolog


Chordata

Activating transcription factor 4

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

Claudin 14

Epilepsy, progressive myoclonic epilepsy, type 2 gene alpha

Fos-like antigen 1

Gap junction membrane channel protein beta 6

Hyaluronan and proteoglycan link protein 1

Transforming growth factor, beta receptor III


Mammalia

Adrenocortical dysplasia

Ameloblastin

Amelogenin X chromosome

BH3 interacting domain death agonist

Colony stimulating factor 2 (granulocyte-macrophage)

Harakiri, BCL2 interacting protein (contains only BH3 domain)

Kit ligand

Leptin

Matrix extracellular phosphoglycoprotein with ASARM motif (bone)

MyoD family inhibitor

Nonagouti

Oncostatin M

Programmed cell death 1

TYRO protein tyrosine kinase binding protein


The first appearance of neural crest genes was then determined using the sequential blast pipeline (Figure 1). The table contains the complete name of neural crest genes emerging in deuterostomia, chordata, vertebrata and mammalia.

Martinez-Morales et al. Genome Biology 2007 8:R36   doi:10.1186/gb-2007-8-3-r36

Open Data