Mobilization of pro-inflammatory lipids in obese Plscr3-deficient mice

David M Mutch^*¹^,3 , Grace O'Maille^*² , William R Wikoff² , Therese Wiedmer¹^,4 , Peter J Sims¹^,4 and Gary Siuzdak²

¹The Scripps Research Institute, Department of Molecular and Experimental Medicine, North Torrey Pines Road, La Jolla, CA 92037, USA

²The Scripps Research Institute, Department of Molecular Biology and the Center for Mass Spectrometry, North Torrey Pines Road, La Jolla, CA 92037, USA

³Current address: INSERM U755 Nutriomique, Paris, F-75004 France; Pierre and Marie Curie - Paris 6 University, Faculty of Medicine, Les Cordeliers, 75004 Paris, France

⁴Current address: Department of Pathology and Laboratory of Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA

author email corresponding author email* Contributed equally

Genome Biology 2007, 8:R38doi:10.1186/gb-2007-8-3-r38


Published:	13 March 2007

Subject areas: Molecular biology, Biochemistry and structural biology, Physiology

Additional files

Additional data file 1:

Name, feature or peak name; M, m/z; T, retention time in units of seconds; mzme, median m/z value; mzmin, minimum m/z value; mzmax, maximum m/z value; rtmed, median retention time in seconds; rtmin, minimum retention time in seconds; rtmax, maximum retention time in seconds; WT, wild-type animal intensity area values; KO3, Plscr3-/- animal intensity area values; KO1, Plscr1-/- animal intensity area values; DKO, double knock-out animals animal intensity area values; the letters a, b, and c following Mouse strain_Mouse Number denote the replicated experimental runs.

Format: TXT Size: 6.3MB Download file

Additional data file 2:

The 19 metabolites associated with PLSCR3 deficiency.

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Additional data file 3:

Sequence information for real-time RT-PCR primers.

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