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Sense-antisense pairs in mammals: functional and evolutionary considerations

Pedro AF Galante1,2, Daniel O Vidal1, Jorge E de Souza1, Anamaria A Camargo1 and Sandro J de Souza1*

1 Ludwig Institute for Cancer Research, São Paulo Branch, Hospital Alemão Oswaldo Cruz, Rua João Juliao 245, 1 andar, São Paulo, SP 01323-903, Brazil

2 Department Of Biochemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748 - sala 351, São Paulo, SP 05508-900, Brazil

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Genome Biology 2007, 8:R40 doi:10.1186/gb-2007-8-3-r40

Published: 19 March 2007

Additional files

Additional data file 1:

Representative GenBank entries for all S-AS pairs in both human and mouse.

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Additional data file 2:

Total number of S-AS pairs by chromosome for both human and mouse.

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Additional data file 3:

Number of clusters and S-AS pairs when a less stringent clustering methodology is applied.

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Additional data file 4:

All possible genomic organizations of S-AS pairs.

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Additional data file 5:

All S-AS pairs conserved between human and mouse using the three strategies described in the text.

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Additional data file 6:

The fraction of S-AS pairs conserved between human and mouse that are classified as 'Fully intronic' and the fraction of conserved S-AS pairs that contain at least one intronless gene.

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Additional data file 7:

All MPSS libraries used in this study.

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Additional data file 8:

The number of cDNA-based pairs that were further confirmed by the MPSS data.

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Additional data file 9:

Chimeric transcripts joining two adjacent genes (SERF2 and HYPK) with a NAT located between them.

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Additional data file 10:

All cases of chimeric transcripts identified in our dataset.

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