Table 2 |
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|
Over-represented TFBSs around the over-expressed promoter in Hepa1-6 compared with liver |
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|
TRANSFAC matrixID |
|Log10(Hepa1-6/liver)| > 0.5 |
P valuea |
Binding factors |
|||
|
|
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|
Hepa1-6 > liver |
Liver > Hepa1-6 |
|||||
|
Number of probes |
% |
Number of probes |
% |
|||
|
|
||||||
|
V$E2F1_Q3 |
87 |
74.4% |
16 |
34.0% |
2.31 × e-06 |
E2f1 |
|
V$SP1_01 |
73 |
62.4% |
11 |
23.4% |
6.04 × e-06 |
Sp1 |
|
V$ETF_Q6 |
62 |
53.0% |
9 |
19.1% |
9.96 × e-05 |
ETFb |
|
V$ZF5_01 |
77 |
65.8% |
16 |
34.0% |
2.50 × e-04 |
Zfp161 |
|
V$CHCH_01 |
81 |
69.2% |
18 |
38.3% |
3.72 × e-04 |
Churc1 |
|
|
||||||
|
Total |
117 |
47 |
||||
|
|
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|
aStatistical significance of the over-representation of each transcription-factor binding site (TFBS) around the over-expressed promoter in Hepa1-6 compared with liver, determined using Fisher's exact probability test. bAlthough TRANSFAC indicated that EGFR-specific transcription factor (ETF) binds to V$ETF_Q6 matrix, there was no report of this interaction in the mouse ortholog. |
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|
Katayama et al. Genome Biology 2007 8:R42 doi:10.1186/gb-2007-8-3-r42 |
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