Table 2

Over-represented TFBSs around the over-expressed promoter in Hepa1-6 compared with liver

TRANSFAC matrixID

|Log10(Hepa1-6/liver)| > 0.5

P valuea

Binding factors


Hepa1-6 > liver

Liver > Hepa1-6

Number of probes

%

Number of probes

%


V$E2F1_Q3

87

74.4%

16

34.0%

2.31 × e-06

E2f1

V$SP1_01

73

62.4%

11

23.4%

6.04 × e-06

Sp1

V$ETF_Q6

62

53.0%

9

19.1%

9.96 × e-05

ETFb

V$ZF5_01

77

65.8%

16

34.0%

2.50 × e-04

Zfp161

V$CHCH_01

81

69.2%

18

38.3%

3.72 × e-04

Churc1


Total

117

47


aStatistical significance of the over-representation of each transcription-factor binding site (TFBS) around the over-expressed promoter in Hepa1-6 compared with liver, determined using Fisher's exact probability test. bAlthough TRANSFAC indicated that EGFR-specific transcription factor (ETF) binds to V$ETF_Q6 matrix, there was no report of this interaction in the mouse ortholog.

Katayama et al. Genome Biology 2007 8:R42   doi:10.1186/gb-2007-8-3-r42

Open Data