Genome Biology

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Evolution of protein complexes by duplication of homomeric interactions

Jose B Pereira-Leal*, Emmanuel D Levy, Christel Kamp and Sarah A Teichmann

Genome Biology 2007, 8:R51 doi:10.1186/gb-2007-8-4-r51

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Research article   Open Access

Evidence for the additions of clustered interacting nodes during the evolution of protein interaction networks from network motifs

Zhongyang Liu, Qijun Liu, Hanchang Sun, Lin Hou, Hao Guo, Yunping Zhu, Dong Li, Fuchu He BMC Evolutionary Biology 2011, 11:133 (20 May 2011)

Proceedings   Open Access

The role of exon shuffling in shaping protein-protein interaction networks

Douglas V Cancherini, Gustavo S França, Sandro J de Souza BMC Genomics 2010, 11(Suppl 5):S11 (22 December 2010)

Research article   Open Access

Duplicability of self-interacting human genes

Åsa Pérez-Bercoff, Takashi Makino, Aoife McLysaght BMC Evolutionary Biology 2010, 10:160 (28 May 2010)

Research article   Open Access

Comparative evolutionary analysis of protein complexes in E. coli and yeast

Adam J Reid, Juan AG Ranea, Christine A Orengo BMC Genomics 2010, 11:79 (1 February 2010)

Research article   Open Access

An evolutionary and structural characterization of mammalian protein complex organization

Philip Wong, Sonja Althammer, Andrea Hildebrand, Andreas Kirschner, Philipp Pagel, Bernd Geissler, Pawel Smialowski, Florian Blöchl, Matthias Oesterheld, Thorsten Schmidt, Normann Strack, Fabian J Theis, Andreas Ruepp, Dmitrij Frishman BMC Genomics 2008, 9:629 (23 December 2008)

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Complex fate of paralogs

Radek Szklarczyk, Martijn A Huynen, Berend Snel BMC Evolutionary Biology 2008, 8:337 (18 December 2008)

The most common fate of duplicated genes is for their products to be found within the same protein complex, with paralogs in separate complexes being more often derived from small-scale duplications than from whole genome duplication.

Research article   Open Access

A simple principle concerning the robustness of protein complex activity to changes in gene expression

Jennifer I Semple, Tanya Vavouri, Ben Lehner BMC Systems Biology 2008, 2:1 (2 January 2008)

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Comparative genomic analysis of the odorant-binding protein family in 12 Drosophila genomes: purifying selection and birth-and-death evolution

Filipe G Vieira, Alejandro Sánchez-Gracia, Julio Rozas Genome Biology 2007, 8:R235 (8 November 2007)

The comparative analysis of the odorant binding protein family in 12 Drosophila genomes allowed the identification of 595 putative family member genes and revealed insights into the evolution of this family in these species.

Research article   Open Access

Multiple domain insertions and losses in the evolution of the Rab prenylation complex

Rita Rasteiro, Jose B Pereira-Leal BMC Evolutionary Biology 2007, 7:140 (17 August 2007)