Table 3

Co-ortholog CNEs that are also conserved in the vicinity of trans-dev paralogs in the human genome

Gene region
Co-ortholog 1
Co-ortholog 2
Gene paralog in the vicinity of the dCNE(s)

BCL11A
CRCNE00002445
CRCNE00004614
BCLL1B

CRCNE00002557
-


CRCNE00002548
CRCNE00004648


CRCNE00002544
CRCNE0004643



CRCNE0004644


CRCNE00002540
-

EBF1
CRCNE00010771
-
EFB3

-
CRCNE00010818


CRCNE00000027
CRCNE00010823


CRCNE00010778
CRCNE00010827


CRCNE00010787
-

EBF1
CRCNE00010772
CRCNE00010820
EBF1/2/3/4
PAX2
CRCNE00000064
CRCNE00000133
PAX8
PAX2
CRCNE00000071
CRCNE00000147
PAX5

CRCNE00000090
CRCNE00000165


CRCNE00000092
CRCNE00000167


CRCNE00000099
CRCNE00000174

SOX1
-
CRCNE00001926
SOX2
ZNF503
CRCNE00010112
CRCNE00004977
ZNF703

CRCNE00010147
CRCNE00004994


CRCNE00010126
CRCNE00005024


CRCNE00010167
-


CRCNE00010170
-


CRCNE00010187
-


CRCNE00010180
-


CRCNE00010176
CRCNE00005013



CRCNE00005015


CRCNE00010165
CRCNE00005011


CRCNE00010161
CRCNE00005008


CRCNE00010046
CRCNE00004906


CRCNE00010156
CRCNE00005003


CRCNE00010120
CRCNE00004986


CNEs in each co-ortholog are referred to by their CONDOR database identifiers [53]. Each CNE was considered duplicated if the human sequence they are conserved to shows significant hit to a sequence elsewhere in the genome through BLAST. Any gene in the vicinity (<1.5 Mb away) of the BLAST hit that is paralogous to genes within a window of the same size around the query CNE is shown in the final column.

Woolfe and Elgar Genome Biology 2007 8:R53   doi:10.1186/gb-2007-8-4-r53