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Resolution: standard / high Figure 3.
Typical plots of T(q) and R(q) in the case of independent experiments. The two independent experiments are simulated under scenario I, structure A, with true differences drawn from a Ga(1, 1) and noise experiment specific of 2 and 2.5, respectively (signal-to-noise ratio = 0.4). The left plot shows the distribution of T(q) and the right one shows the distribution of R(q) with Bayesian credibility intervals at 95%. T(q) follows a horizontal line of height 1 (independence between the lists) and presents instability for small p values (left tail). The Bayesian model does not present any significant threshold for which R(q) deviates from 1 and the CI95 always includes 1.
Blangiardo and Richardson Genome Biology 2007 8:R54 doi:10.1186/gb-2007-8-4-r54 |