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Results from high-fat diet experiment |
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| Joint Bayesian model |
Hwang et al.'s method |
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|
|
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| Rules |
q |
R(q) |
O11 |
O1+ |
O+1 |
CI95 |
DE |
nonDE |
|
|
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| Max |
0.02 |
3.83 |
49 |
1,893 |
85 |
2.72-4.68 |
3,746 |
8,742 |
| Double |
0.07 |
2.04 |
226 |
3,059 |
452 |
1.90-2.21 |
3,746 |
8,742 |
|
The joint model returns R(qmax) = 3.83 with an associated credibility interval [3.17-4.44]. The conditional model shows the same results (data not reported). The R(q2) is 2.04 and the CI is 1.90-2.21. The procedure indicates clearly a significant association between the two lists. Hwang et al.'s method calls 3,746 genes as differentially expressed (DE). All the genes called by our method are included in their list. | ||||||||
Blangiardo and Richardson Genome Biology 2007 8:R54 doi:10.1186/gb-2007-8-4-r54 |
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