Genome Biology

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Open Access Research

Ancient papillomavirus-host co-speciation in Felidae

Annabel Rector1, Philippe Lemey1,2, Ruth Tachezy3, Sara Mostmans1, Shin-Je Ghim4, Koenraad Van Doorslaer1,5, Melody Roelke6, Mitchell Bush7, Richard J Montali8, Janis Joslin9, Robert D Burk5, Alfred B Jenson4, John P Sundberg10, Beth Shapiro2 and Marc Van Ranst1*

Author Affiliations

1 Laboratory of Clinical & Epidemiological Virology, Rega Institute for Medical Research, University of Leuven, Minderbroedersstraat, B3000 Leuven, Belgium

2 Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK

3 Department of Experimental Virology, Institute of Hematology and Blood Transfusion, U Nemocnice, 128 22 Prague, Czech Republic

4 The Brown Cancer Center, University of Louisville, South Jackson Street, Louisville, KY 40202, USA

5 Department of Epidemiology and Social Medicine, Comprehensive Cancer Center, Albert Einstein College of Medicine, Morris Park Avenue, Bronx, NY 10461, USA

6 Basic Research Program-SAIC Frederick-National Cancer Institute, Building 560, Frederick, MD 21702-1201, USA

7 National Zoological Park, Smithsonian Conservation and Research Center, Remount Road, Front Royal, VA 22630, USA

8 East Wakefield Drive, Alexandria, Virginia 22307, USA

9 Phoenix Zoo, Galvin Parkway, Phoenix, AZ 85008, USA

10 The Jackson Laboratory, Main Street, Bar Harbor, MA 04609-1500, USA

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Genome Biology 2007, 8:R57 doi:10.1186/gb-2007-8-4-r57

Published: 12 April 2007

Additional files

Additional data file 1:

Table indicating the nucleotide position of the start of the ORF, start codon, and stop codon, the nucleotide and amino acid count of the ORFs and the predicted proteins respectively, and the predicted molecular weight of the putative proteins, for the different ORFs of the feline PVs LrPV1, PcPV1, PlpPV1, UuPV1, and FdPV1.

Format: DOC Size: 86KB Download file

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Open Data

Additional data file 2:

Table indicating the percentages nucleotide and amino acid similarity of different ORFs of the feline PVs mutually and with the corresponding ORFs of COPV, HPV1, HPV5, HPV16, and BPV1.

Format: DOC Size: 72KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional data file 3:

Nucleotide sequence alignment of the NCR2 of the feline PVs LrPV1, PcPV1, PlpPV1, UuPV1, and FdPV1, from the stop codon of E2 to the start codon of L2. Nucleotides are shaded according to the degree of conservation (black = 100% conserved; dark gray = 80% to 99% conserved; light gray = 60% to 79% conserved; no shade = <60% conserved).

Format: EPS Size: 9.6MB Download file

Open Data

Additional data file 4:

Concatenated alignment of the E6, E7, E1, E2, L2, and L1 ORFs of the members of the genus λ-PV, used for phylogenetic reconstruction and calculation of evolutionary rates.

Format: NEX Size: 54KB Download file

Open Data

Additional data file 5:

Alignment of the URR (NCR1) of the feline PVs, used for calculation of the URR evolutionary rate.

Format: NEX Size: 3KB Download file

Open Data